TV series example of the word

The Big Bang Theory Season 6, Episode 24
...pick up a pen and get it all out in my journal. I mean...

Breaking Bad Season 3, Episode 11
What do you mean? How much have you sold?

The Big Bang Theory Season 6, Episode 8
What the hell does that mean?

Game of Thrones Season 6, Episode 3
And what does that mean to you?

Game of Thrones Season 5, Episode 2
And your sister is a mean person.