TV series example of the word

The Big Bang Theory Season 7, Episode 5
with his significant other.

The Big Bang Theory Season 1, Episode 1
Significant improvement over the old neighbor.

The Big Bang Theory Season 10, Episode 7
Gentlemen, please! This is a significant decision.

The Big Bang Theory Season 10, Episode 4
Well, you've lived with your significant other for some time.

Breaking Bad Season 2, Episode 10
But there's been a significant reduction in the tumors.